HeartShare - Harmonized Academic Observational Data

HeartShare - Harmonized Academic Observational Data

Summary of variables at baseline

2024-09-24

This report is was prepared using data from: phenotypeset_read_all2.csv.

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Baseline Summary Tables

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On ACE/ARB

Variable used: acearb

Additional label: ACEI/ARB

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	432 (7.5%)	5,363 (92.5%)	5,795 (100.0%)
FHS	297 (2.1%)	29 (0.2%)	13,642 (97.7%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	1,233 (18.1%)	5,581 (81.9%)	6,814 (100.0%)
Total	297 (0.7%)	1,694 (3.7%)	43,473 (95.6%)	45,464 (100.0%)

On ACE-inhibitor

Variable used: acei

Additional label: ACEI

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,351 (92.3%)	432 (7.5%)	12 (0.2%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	884 (13.0%)	5,930 (87.0%)	6,814 (100.0%)
Total	5,351 (11.8%)	1,316 (2.9%)	38,797 (85.3%)	45,464 (100.0%)

Activities of daily living score

Variable used: adl_score

Additional label: NA

Study	0	1	2	3	4	5	6	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,316 (91.7%)	282 (4.9%)	125 (2.2%)	40 (0.7%)	17 (0.3%)	3 (0.1%)	2 (0.0%)	10 (0.2%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	5,316 (11.7%)	282 (0.6%)	125 (0.3%)	40 (0.1%)	17 (0.0%)	3 (0.0%)	2 (0.0%)	39,679 (87.3%)	45,464 (100.0%)

Adiponectin

Variable used: adpnctn

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	137	351.91	2689.91	4232.3	6731.67	53366.76	5397.14	4276.05
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41718	351.91	2689.91	4232.3	6731.67	53366.76	5397.14	4276.05

Atrial fibrillation/flutter

Variable used: af

Additional label: AF/FLU

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	33 (0.2%)	14,971 (99.8%)	15,004 (100.0%)
CHS	4,163 (71.8%)	227 (3.9%)	1,405 (24.2%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	18 (0.5%)	3,865 (99.5%)	3,883 (100.0%)
MESA	6,814 (100.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)
Total	10,977 (24.1%)	278 (0.6%)	34,209 (75.2%)	45,464 (100.0%)

Age category

Variable used: age_cat

Additional label: Age, yrs

Study	< 55	55-75	75+	Unknown	Total
ARIC	7,827 (52.2%)	6,421 (42.8%)	0 (0.0%)	756 (5.0%)	15,004 (100.0%)
CHS	0 (0.0%)	4,367 (75.4%)	1,428 (24.6%)	0 (0.0%)	5,795 (100.0%)
FHS	8,229 (58.9%)	839 (6.0%)	0 (0.0%)	4,900 (35.1%)	13,968 (100.0%)
JHS	1,821 (46.9%)	1,739 (44.8%)	186 (4.8%)	137 (3.5%)	3,883 (100.0%)
MESA	1,947 (28.6%)	3,703 (54.3%)	806 (11.8%)	358 (5.3%)	6,814 (100.0%)
Total	19,824 (43.6%)	17,069 (37.5%)	2,420 (5.3%)	6,151 (13.5%)	45,464 (100.0%)

Age value

Variable used: age_val

Additional label: Age, yrs

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	0	44	49	54	59	66	54.24	5.76
CHS	5795	0	64	66	70	74	88	71.33	5.57
FHS	13968	4727	5	34	41	49	74	41.02	10.38
JHS	3883	0	20	45	56	65	95	55.20	12.82
MESA	6814	0	44	53	62	70	84	62.15	10.23
Overall	45464	4727	5	47	55	64	95	55.09	12.86

Drinks per week - alcohol

Variable used: alcohol_week_val

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	100	0	0	0.00	3.10	132.57	3.07	6.98
CHS	5795	23	0	0	0.02	1.25	630.00	2.59	10.81
FHS	13968	7591	0	0	3.00	8.00	100.00	6.70	10.05
JHS	3883	121	0	0	0.00	0.50	70.00	1.54	5.08
MESA	6814	1461	0	0	2.00	6.00	99.00	5.07	9.29
Overall	45464	9296	0	0	0.04	4.00	630.00	3.77	8.64

Aldosterone-renin ratio

Variable used: aldo_renin

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	10020	0.13	3.99	6.61	11.19	Inf	Inf	NaN
JHS	3883	2103	0.04	4.00	9.50	17.00	131.58	13.22	14.19
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	39736	0.04	4.00	7.04	12.80	Inf	Inf	NaN

Anemia

Variable used: anemia

Additional label: Anemia

Study	No	Yes	Unknown	Total
ARIC	13,544 (90.3%)	1,163 (7.8%)	297 (2.0%)	15,004 (100.0%)
CHS	5,166 (89.1%)	522 (9.0%)	107 (1.8%)	5,795 (100.0%)
FHS	5,781 (41.4%)	617 (4.4%)	7,570 (54.2%)	13,968 (100.0%)
JHS	2,801 (72.1%)	899 (23.2%)	183 (4.7%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	27,292 (60.0%)	3,201 (7.0%)	14,971 (32.9%)	45,464 (100.0%)

Angina

Variable used: angina

Additional label: Angina

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	4,663 (80.5%)	714 (12.3%)	418 (7.2%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	4,663 (10.3%)	714 (1.6%)	40,087 (88.2%)	45,464 (100.0%)

On antiarrhythmic

Variable used: antiarrhy

Additional label: Antiarrhythmic

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	194 (3.3%)	5,601 (96.7%)	5,795 (100.0%)
FHS	324 (2.3%)	2 (0.0%)	13,642 (97.7%)	13,968 (100.0%)
JHS	3,673 (94.6%)	172 (4.4%)	38 (1.0%)	3,883 (100.0%)
MESA	6,775 (99.4%)	36 (0.5%)	3 (0.0%)	6,814 (100.0%)
Total	10,772 (23.7%)	404 (0.9%)	34,288 (75.4%)	45,464 (100.0%)

On antidepressant

Variable used: antidepress

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	232 (4.0%)	5,563 (96.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	6,311 (92.6%)	500 (7.3%)	3 (0.0%)	6,814 (100.0%)
Total	6,311 (13.9%)	732 (1.6%)	38,421 (84.5%)	45,464 (100.0%)

On anti-platelet

Variable used: antipltlt

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,783 (99.8%)	0 (0.0%)	12 (0.2%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	6,794 (99.7%)	17 (0.2%)	3 (0.0%)	6,814 (100.0%)
Total	12,577 (27.7%)	17 (0.0%)	32,870 (72.3%)	45,464 (100.0%)

Aortic regurgitation

Variable used: aortic_regurg

Additional label: AR

Study	Normal/Mild	Moderate/severe	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	951 (16.4%)	66 (1.1%)	4,778 (82.5%)	5,795 (100.0%)
FHS	4,402 (31.5%)	18 (0.1%)	9,548 (68.4%)	13,968 (100.0%)
JHS	3,664 (94.4%)	31 (0.8%)	188 (4.8%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	9,017 (19.8%)	115 (0.3%)	36,332 (79.9%)	45,464 (100.0%)

On ARB

Variable used: arb

Additional label: ARB

Study	Yes	Unknown	Total
ARIC	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	362 (5.3%)	6,452 (94.7%)	6,814 (100.0%)
Total	362 (0.8%)	45,102 (99.2%)	45,464 (100.0%)

On aspirin

Variable used: ASA

Additional label: ASA

Study	No	Yes	Unknown	Total
ARIC	7,919 (52.8%)	6,955 (46.4%)	130 (0.9%)	15,004 (100.0%)
CHS	5,589 (96.4%)	194 (3.3%)	12 (0.2%)	5,795 (100.0%)
FHS	273 (2.0%)	24 (0.2%)	13,671 (97.9%)	13,968 (100.0%)
JHS	925 (23.8%)	936 (24.1%)	2,022 (52.1%)	3,883 (100.0%)
MESA	5,109 (75.0%)	1,702 (25.0%)	3 (0.0%)	6,814 (100.0%)
Total	19,815 (43.6%)	9,811 (21.6%)	15,838 (34.8%)	45,464 (100.0%)

ASCVD 10-yr risk score

Variable used: ascvd

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	878	0	0.04	0.09	0.16	0.68	0.12	0.1
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	42459	0	0.04	0.09	0.16	0.68	0.12	0.1

A wave value

Variable used: awave

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	9546	23.02	43.54	50.46	58.64	138.32	51.84	11.91
JHS	3883	383	0.15	0.67	0.80	0.95	1.63	0.81	0.20
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	37542	0.15	0.83	38.24	51.81	138.32	29.30	26.86

On beta-blocker

Variable used: betab

Additional label: BB

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,040 (87.0%)	743 (12.8%)	12 (0.2%)	5,795 (100.0%)
FHS	306 (2.2%)	18 (0.1%)	13,644 (97.7%)	13,968 (100.0%)
JHS	3,183 (82.0%)	418 (10.8%)	282 (7.3%)	3,883 (100.0%)
MESA	0 (0.0%)	649 (9.5%)	6,165 (90.5%)	6,814 (100.0%)
Total	8,529 (18.8%)	1,828 (4.0%)	35,107 (77.2%)	45,464 (100.0%)

Black tea range

Variable used: black_tea_cat

Additional label: NA

Study	< 1 per week	> 1/day	1-6/week	Never	Unknown	Total
ARIC	1,777 (11.8%)	3,590 (23.9%)	3,840 (25.6%)	5,755 (38.4%)	42 (0.3%)	15,004 (100.0%)
CHS	1,494 (25.8%)	1,246 (21.5%)	1,110 (19.2%)	1,215 (21.0%)	730 (12.6%)	5,795 (100.0%)
FHS	748 (5.4%)	541 (3.9%)	867 (6.2%)	1,917 (13.7%)	9,895 (70.8%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	823 (12.1%)	651 (9.6%)	981 (14.4%)	3,603 (52.9%)	756 (11.1%)	6,814 (100.0%)
Total	4,842 (10.7%)	6,028 (13.3%)	6,798 (15.0%)	12,490 (27.5%)	15,306 (33.7%)	45,464 (100.0%)

Black tea - daily servings

Variable used: black_tea_daily

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	42	0	0	0.07	0.80	7	0.57	1.06
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	10297	0	0	0.07	0.14	6	0.32	0.71
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	577	0	0	0.00	0.22	9	0.31	0.86
Overall	45464	20594	0	0	0.07	0.43	9	0.47	0.98

BMI

Variable used: bmi

Additional label: BMI

Study	Underweight	Normal	Overweight	Obese	Unknown	Total
ARIC	135 (0.9%)	4,822 (32.1%)	5,909 (39.4%)	4,114 (27.4%)	24 (0.2%)	15,004 (100.0%)
CHS	0 (0.0%)	2,230 (38.5%)	2,399 (41.4%)	1,147 (19.8%)	19 (0.3%)	5,795 (100.0%)
FHS	174 (1.2%)	4,476 (32.0%)	3,349 (24.0%)	1,223 (8.8%)	4,746 (34.0%)	13,968 (100.0%)
JHS	14 (0.4%)	529 (13.6%)	1,238 (31.9%)	2,088 (53.8%)	14 (0.4%)	3,883 (100.0%)
MESA	49 (0.7%)	1,905 (28.0%)	2,667 (39.1%)	2,193 (32.2%)	0 (0.0%)	6,814 (100.0%)
Total	372 (0.8%)	13,962 (30.7%)	15,562 (34.2%)	10,765 (23.7%)	4,803 (10.6%)	45,464 (100.0%)

BMI value

Variable used: bmi_val

Additional label: BMI, kg/m2

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	24	14.20	24.03	26.88	30.44	65.91	27.70	5.36
CHS	5795	19	20.20	23.52	26.09	29.16	35.30	26.58	4.09
FHS	13968	4744	13.52	22.49	24.95	27.85	56.80	25.48	4.38
JHS	3883	10	16.02	26.92	30.65	35.56	91.80	31.88	7.29
MESA	6814	0	16.04	24.55	27.61	31.18	54.50	28.33	5.43
Overall	45464	4797	13.52	23.75	26.69	30.29	91.80	27.54	5.51

On BP medications

Variable used: bp_meds

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	10,383 (69.2%)	4,614 (30.8%)	7 (0.0%)	15,004 (100.0%)
CHS	3,033 (52.3%)	2,750 (47.5%)	12 (0.2%)	5,795 (100.0%)
FHS	8,056 (57.7%)	642 (4.6%)	5,270 (37.7%)	13,968 (100.0%)
JHS	1,785 (46.0%)	2,065 (53.2%)	33 (0.8%)	3,883 (100.0%)
MESA	4,275 (62.7%)	2,536 (37.2%)	3 (0.0%)	6,814 (100.0%)
Total	27,532 (60.6%)	12,607 (27.7%)	5,325 (11.7%)	45,464 (100.0%)

Body surface area

Variable used: bsa

Additional label: BSA, m2

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	10	1.34	1.84	1.99	2.15	3.28	2.00	0.23
MESA	6814	0	1.26	1.70	1.85	2.02	2.60	1.86	0.23
Overall	45464	34777	1.26	1.75	1.91	2.07	3.28	1.91	0.24

Prior CABG

Variable used: cabg

Additional label: CABG

Study	No	Yes	Unknown	Total
ARIC	162 (1.1%)	232 (1.5%)	14,610 (97.4%)	15,004 (100.0%)
CHS	5,507 (95.0%)	245 (4.2%)	43 (0.7%)	5,795 (100.0%)
FHS	4,055 (29.0%)	7 (0.1%)	9,906 (70.9%)	13,968 (100.0%)
JHS	95 (2.4%)	53 (1.4%)	3,735 (96.2%)	3,883 (100.0%)
MESA	6,814 (100.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)
Total	16,633 (36.6%)	537 (1.2%)	28,294 (62.2%)	45,464 (100.0%)

On calcium channel blocker

Variable used: cachblk

Additional label: CCB

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	782 (13.5%)	5,013 (86.5%)	5,795 (100.0%)
FHS	300 (2.1%)	25 (0.2%)	13,643 (97.7%)	13,968 (100.0%)
JHS	2,890 (74.4%)	726 (18.7%)	267 (6.9%)	3,883 (100.0%)
MESA	5,973 (87.7%)	838 (12.3%)	3 (0.0%)	6,814 (100.0%)
Total	9,163 (20.2%)	2,371 (5.2%)	33,930 (74.6%)	45,464 (100.0%)

Coronary artery disease

Variable used: cad

Additional label: CAD

Study	No	Yes	Unknown	Total
ARIC	13,925 (92.8%)	749 (5.0%)	330 (2.2%)	15,004 (100.0%)
CHS	0 (0.0%)	1,137 (19.6%)	4,658 (80.4%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	3,579 (92.2%)	304 (7.8%)	0 (0.0%)	3,883 (100.0%)
MESA	6,814 (100.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)
Total	24,318 (53.5%)	2,190 (4.8%)	18,956 (41.7%)	45,464 (100.0%)

Caffeine daily

Variable used: caff_daily

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	578	0	41.09	125.31	290.32	1352.68	183.77	204.63
Overall	45464	39228	0	41.09	125.31	290.32	1352.68	183.77	204.63

Caffeinated soda range

Variable used: caff_soda_cat

Additional label: NA

Study	< 1 per week	> 1/day	1-6/week	Never	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	665 (4.8%)	299 (2.1%)	883 (6.3%)	2,266 (16.2%)	9,855 (70.6%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	665 (1.5%)	299 (0.7%)	883 (1.9%)	2,266 (5.0%)	41,351 (91.0%)	45,464 (100.0%)

Caffeinated soda - daily servings

Variable used: caff_soda_daily

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	9855	0	0	0	0.14	7	0.23	0.64
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41351	0	0	0	0.14	7	0.23	0.64

Caffeinated tea - daily servings

Variable used: caff_tea_daily

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13643	0	0	0	0	6	0.44	0.94
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	45139	0	0	0	0	6	0.44	0.94

Calories daily

Variable used: cal_daily

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	36	81.88	1170.40	1521.57	1956.10	21779.21	1635.20	717.39
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	9790	132.78	1561.74	2000.00	2497.49	11859.88	2123.99	850.55
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	578	203.42	974.50	1360.71	1877.10	8383.49	1530.82	804.45
Overall	45464	20082	81.88	1164.06	1559.43	2048.21	21779.21	1690.01	787.73

Cancer

Variable used: cancer

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	14,101 (94.0%)	847 (5.6%)	56 (0.4%)	15,004 (100.0%)
CHS	4,958 (85.6%)	827 (14.3%)	10 (0.2%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	6,262 (91.9%)	536 (7.9%)	16 (0.2%)	6,814 (100.0%)
Total	25,321 (55.7%)	2,210 (4.9%)	17,933 (39.4%)	45,464 (100.0%)

Feels cared for by partner

Variable used: cared_for_by_partner

Additional label: NA

Study	A great deal	A little	Not at all	Quite a bit	Some	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	1,308 (33.7%)	101 (2.6%)	46 (1.2%)	440 (11.3%)	308 (7.9%)	1,680 (43.3%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	1,308 (2.9%)	101 (0.2%)	46 (0.1%)	440 (1.0%)	308 (0.7%)	43,261 (95.2%)	45,464 (100.0%)

CES-D10 score

Variable used: cesd10

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	10	0	1	3.33	7	29	4.71	4.6
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	39679	0	1	3.33	7	29	4.71	4.6

CES-D20 score

Variable used: cesd20

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	9815	0	12	14	18	182	16.72	12.97
JHS	3883	1343	0	5	10	15	48	11.16	8.20
MESA	6814	36	0	2	6	10	53	7.58	7.59
Overall	45464	31993	0	4	10	15	182	11.07	10.46

Chronic kidney disease stage

Variable used: ckd

Additional label: CKD

Study	Stage 1	Stage 2	Stage 3	Stage 4/5	Unknown	Total
ARIC	12,396 (82.6%)	2,274 (15.2%)	163 (1.1%)	34 (0.2%)	137 (0.9%)	15,004 (100.0%)
CHS	1,365 (23.6%)	3,101 (53.5%)	1,205 (20.8%)	55 (0.9%)	69 (1.2%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	2,315 (59.6%)	1,270 (32.7%)	213 (5.5%)	41 (1.1%)	44 (1.1%)	3,883 (100.0%)
MESA	1,587 (23.3%)	4,317 (63.4%)	852 (12.5%)	33 (0.5%)	25 (0.4%)	6,814 (100.0%)
Total	17,663 (38.9%)	10,962 (24.1%)	2,433 (5.4%)	163 (0.4%)	14,243 (31.3%)	45,464 (100.0%)

Cocaine use

Variable used: cocaine

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	3,693 (95.1%)	169 (4.4%)	21 (0.5%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	3,693 (8.1%)	169 (0.4%)	41,602 (91.5%)	45,464 (100.0%)

Coffee range

Variable used: coffee_cat

Additional label: NA

Study	< 1 per week	> 1/day	1-6/week	Never	Unknown	Total
ARIC	587 (3.9%)	8,902 (59.3%)	1,468 (9.8%)	4,004 (26.7%)	43 (0.3%)	15,004 (100.0%)
CHS	668 (11.5%)	2,167 (37.4%)	458 (7.9%)	1,766 (30.5%)	736 (12.7%)	5,795 (100.0%)
FHS	168 (1.2%)	2,219 (15.9%)	604 (4.3%)	1,128 (8.1%)	9,849 (70.5%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	445 (6.5%)	2,742 (40.2%)	1,367 (20.1%)	1,571 (23.1%)	689 (10.1%)	6,814 (100.0%)
Total	1,868 (4.1%)	16,030 (35.3%)	3,897 (8.6%)	8,469 (18.6%)	15,200 (33.4%)	45,464 (100.0%)

Coffee - daily servings

Variable used: coffee_daily

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	43	0	0	1.0	2.5	7	1.80	2.07
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	577	0	0	0.5	1.5	9	1.18	1.57
Overall	45464	24266	0	0	1.0	2.5	9	1.62	1.96

Health compared to peers

Variable used: compare_health

Additional label: NA

Study	Excellent	Fair	Good	Poor	Unknown	Total
ARIC	4,991 (33.3%)	2,486 (16.6%)	6,989 (46.6%)	530 (3.5%)	8 (0.1%)	15,004 (100.0%)
CHS	3,084 (53.2%)	2,107 (36.4%)	0 (0.0%)	191 (3.3%)	413 (7.1%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	8,075 (17.8%)	4,593 (10.1%)	6,989 (15.4%)	721 (1.6%)	25,086 (55.2%)	45,464 (100.0%)

COPD

Variable used: copd

Additional label: COPD

Study	No	Yes	Unknown	Total
ARIC	14,182 (94.5%)	744 (5.0%)	78 (0.5%)	15,004 (100.0%)
CHS	4,842 (83.6%)	741 (12.8%)	212 (3.7%)	5,795 (100.0%)
FHS	4,511 (32.3%)	18 (0.1%)	9,439 (67.6%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	6,702 (98.4%)	104 (1.5%)	8 (0.1%)	6,814 (100.0%)
Total	30,237 (66.5%)	1,607 (3.5%)	13,620 (30.0%)	45,464 (100.0%)

Coenzyme Q - frequency

Variable used: coq

Additional label: NA

Study	1	2	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	1 (0.0%)	142 (2.1%)	6,671 (97.9%)	6,814 (100.0%)
Total	1 (0.0%)	142 (0.3%)	45,321 (99.7%)	45,464 (100.0%)

Cortisol

Variable used: cortisol

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	68	0.4	6.9	9.2	12.1	36.3	9.9	4.15
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41649	0.4	6.9	9.2	12.1	36.3	9.9	4.15

On COX-2 inhibitor

Variable used: cox2i

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,783 (99.8%)	0 (0.0%)	12 (0.2%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	6,339 (93.0%)	472 (6.9%)	3 (0.0%)	6,814 (100.0%)
Total	12,122 (26.7%)	472 (1.0%)	32,870 (72.3%)	45,464 (100.0%)

Creatinine clearance

Variable used: crcl

Additional label: CrCl

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	137	2.32	94.71	102.98	111.29	309.34	102.26	15.86
CHS	5795	69	5.88	63.69	76.47	89.93	239.06	78.21	23.38
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	44	4.16	80.49	96.31	109.66	152.63	94.00	22.46
MESA	6814	25	5.24	67.11	78.06	88.99	175.87	78.04	16.34
Overall	45464	14243	2.32	76.72	94.30	106.38	309.34	91.57	21.63

Creatinine clearance < 30

Variable used: crcl_30

Additional label: CrCl < 30

Study	> 30	< 30	Unknown	Total
ARIC	14,833 (98.9%)	34 (0.2%)	137 (0.9%)	15,004 (100.0%)
CHS	5,671 (97.9%)	55 (0.9%)	69 (1.2%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	3,798 (97.8%)	41 (1.1%)	44 (1.1%)	3,883 (100.0%)
MESA	6,756 (99.1%)	33 (0.5%)	25 (0.4%)	6,814 (100.0%)
Total	31,058 (68.3%)	163 (0.4%)	14,243 (31.3%)	45,464 (100.0%)

High sensitivity C-reactive protein

Variable used: crp_val

Additional label: CRP

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	82	0.09	1.28	2.54	4.50	157.55	4.80	8.32
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	63	0.00	0.11	0.27	0.58	33.80	0.53	0.96
MESA	6814	52	0.15	0.84	1.92	4.26	97.40	3.78	5.89
Overall	45464	29169	0.00	0.54	1.52	3.58	157.55	3.38	6.45

Current smoker

Variable used: cur_smoke

Additional label: Active smoker

Study	No	Yes	Unknown	Total
ARIC	11,030 (73.5%)	3,959 (26.4%)	15 (0.1%)	15,004 (100.0%)
CHS	5,091 (87.9%)	698 (12.0%)	6 (0.1%)	5,795 (100.0%)
FHS	7,382 (52.8%)	4,018 (28.8%)	2,568 (18.4%)	13,968 (100.0%)
JHS	3,337 (85.9%)	510 (13.1%)	36 (0.9%)	3,883 (100.0%)
MESA	5,905 (86.7%)	887 (13.0%)	22 (0.3%)	6,814 (100.0%)
Total	32,745 (72.0%)	10,072 (22.2%)	2,647 (5.8%)	45,464 (100.0%)

Fall asleep during day

Variable used: day_sleep

Additional label: NA

Study	Almost always	Never	Often	Seldom	Sometimes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	178 (4.6%)	1,331 (34.3%)	316 (8.1%)	585 (15.1%)	1,447 (37.3%)	26 (0.7%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	178 (0.4%)	1,331 (2.9%)	316 (0.7%)	585 (1.3%)	1,447 (3.2%)	41,607 (91.5%)	45,464 (100.0%)

Diastolic blood pressure

Variable used: dbp_cat

Additional label: DBP

Study	< 60	60-80	80+	Unknown	Total
ARIC	1,208 (8.1%)	9,419 (62.8%)	3,635 (24.2%)	742 (4.9%)	15,004 (100.0%)
CHS	910 (15.7%)	3,485 (60.1%)	1,127 (19.4%)	273 (4.7%)	5,795 (100.0%)
FHS	289 (2.1%)	6,487 (46.4%)	5,831 (41.7%)	1,361 (9.7%)	13,968 (100.0%)
JHS	111 (2.9%)	2,552 (65.7%)	1,209 (31.1%)	11 (0.3%)	3,883 (100.0%)
MESA	780 (11.4%)	4,516 (66.3%)	1,372 (20.1%)	146 (2.1%)	6,814 (100.0%)
Total	3,298 (7.3%)	26,459 (58.2%)	13,174 (29.0%)	2,533 (5.6%)	45,464 (100.0%)

Diastolic blood pressure value

Variable used: dbp_val

Additional label: DBP, mm Hg

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	13	0.00	66.00	73.00	80.00	144.0	73.70	11.36
CHS	5795	18	40.00	63.00	70.44	78.00	116.0	70.75	11.41
FHS	13968	171	38.00	72.00	79.00	87.00	158.0	79.85	11.91
JHS	3883	11	42.67	69.24	75.88	81.69	112.4	75.67	8.72
MESA	6814	3	37.00	65.00	71.50	78.50	118.5	71.91	10.26
Overall	45464	216	0.00	67.50	74.22	82.00	158.0	75.10	11.68

Decaf coffee range

Variable used: decaf_coffee_cat

Additional label: NA

Study	< 1 per week	< 1/week	> 1/day	1-6/week	Never	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	741 (12.8%)	1,826 (31.5%)	555 (9.6%)	1,939 (33.5%)	734 (12.7%)	5,795 (100.0%)
FHS	332 (2.4%)	0 (0.0%)	309 (2.2%)	366 (2.6%)	3,090 (22.1%)	9,871 (70.7%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	332 (0.7%)	741 (1.6%)	2,135 (4.7%)	921 (2.0%)	5,029 (11.1%)	36,306 (79.9%)	45,464 (100.0%)

Decaffeinated soda range

Variable used: decaf_soda_cat

Additional label: NA

Study	< 1 per week	> 1/day	1-6/week	Never	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	331 (2.4%)	59 (0.4%)	302 (2.2%)	3,400 (24.3%)	9,876 (70.7%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	331 (0.7%)	59 (0.1%)	302 (0.7%)	3,400 (7.5%)	41,372 (91.0%)	45,464 (100.0%)

Decaffeinated soda - daily servings

Variable used: decaf_soda_val

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	9876	0	0	0	0	7	0.05	0.29
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41372	0	0	0	0	7	0.05	0.29

Decaffeinated tea - daily servings

Variable used: decaf_tea_val

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13643	0	0	0	0	4	0.11	0.44
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	45139	0	0	0	0	4	0.11	0.44

Mitral E decel time

Variable used: decel_time

Additional label: MV decel time

Study	<150	150-220	220+	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	37 (0.3%)	3,018 (21.6%)	1,298 (9.3%)	9,615 (68.8%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	37 (0.1%)	3,018 (6.6%)	1,298 (2.9%)	41,111 (90.4%)	45,464 (100.0%)

Mitral E decel time value

Variable used: decel_time_val

Additional label: MV decel time

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	9546	106	190	206	224	362	208.6	27.76
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41042	106	190	206	224	362	208.6	27.76

Depression - CES-D

Variable used: depression

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	4,543 (78.4%)	1,007 (17.4%)	245 (4.2%)	5,795 (100.0%)
FHS	2,526 (18.1%)	1,320 (9.5%)	10,122 (72.5%)	13,968 (100.0%)
JHS	1,946 (50.1%)	530 (13.6%)	1,407 (36.2%)	3,883 (100.0%)
MESA	5,904 (86.6%)	762 (11.2%)	148 (2.2%)	6,814 (100.0%)
Total	14,919 (32.8%)	3,619 (8.0%)	26,926 (59.2%)	45,464 (100.0%)

Diet soda range

Variable used: diet_soda_cat

Additional label: NA

Study	< 1 per week	> 1/day	1-6/week	Never	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	1,200 (20.7%)	527 (9.1%)	820 (14.2%)	2,513 (43.4%)	735 (12.7%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	1,200 (2.6%)	527 (1.2%)	820 (1.8%)	2,513 (5.5%)	40,404 (88.9%)	45,464 (100.0%)

Diet soda - daily servings

Variable used: diet_soda_val

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	577	0	0	0	0.43	9	0.45	1.09
Overall	45464	39227	0	0	0	0.43	9	0.45	1.09

On digoxin

Variable used: digoxin

Additional label: Digoxin

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,293 (91.3%)	490 (8.5%)	12 (0.2%)	5,795 (100.0%)
FHS	8,904 (63.7%)	132 (0.9%)	4,932 (35.3%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	6,785 (99.6%)	26 (0.4%)	3 (0.0%)	6,814 (100.0%)
Total	20,982 (46.2%)	648 (1.4%)	23,834 (52.4%)	45,464 (100.0%)

On diuretic

Variable used: diuretic

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	4,096 (70.7%)	1,687 (29.1%)	12 (0.2%)	5,795 (100.0%)
FHS	3,770 (27.0%)	63 (0.5%)	10,135 (72.6%)	13,968 (100.0%)
JHS	2,354 (60.6%)	1,290 (33.2%)	239 (6.2%)	3,883 (100.0%)
MESA	5,894 (86.5%)	917 (13.5%)	3 (0.0%)	6,814 (100.0%)
Total	16,114 (35.4%)	3,957 (8.7%)	25,393 (55.9%)	45,464 (100.0%)

Diabetes mellitus

Variable used: dm

Additional label: DM

Study	No	Yes	Unknown	Total
ARIC	13,061 (87.1%)	1,808 (12.1%)	135 (0.9%)	15,004 (100.0%)
CHS	4,786 (82.6%)	946 (16.3%)	63 (1.1%)	5,795 (100.0%)
FHS	8,673 (62.1%)	263 (1.9%)	5,032 (36.0%)	13,968 (100.0%)
JHS	3,849 (99.1%)	0 (0.0%)	34 (0.9%)	3,883 (100.0%)
MESA	5,931 (87.0%)	859 (12.6%)	24 (0.4%)	6,814 (100.0%)
Total	36,300 (79.8%)	3,876 (8.5%)	5,288 (11.6%)	45,464 (100.0%)

On DM therapy

Variable used: dm_meds

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	499 (8.6%)	5,296 (91.4%)	5,795 (100.0%)
FHS	9,138 (65.4%)	83 (0.6%)	4,747 (34.0%)	13,968 (100.0%)
JHS	3,189 (82.1%)	657 (16.9%)	37 (1.0%)	3,883 (100.0%)
MESA	0 (0.0%)	655 (9.6%)	6,159 (90.4%)	6,814 (100.0%)
Total	12,327 (27.1%)	1,894 (4.2%)	31,243 (68.7%)	45,464 (100.0%)

Diabetes mellitus type

Variable used: dm_type

Additional label: NA

Study	Type 1	Type 2	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	10 (0.1%)	670 (9.8%)	6,134 (90.0%)	6,814 (100.0%)
Total	10 (0.0%)	670 (1.5%)	44,784 (98.5%)	45,464 (100.0%)

Dark green vegetables - daily servings

Variable used: drkgreen_veg_daily

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	359	0	0.15	0.26	0.42	5.35	0.35	0.34
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41940	0	0.15	0.26	0.42	5.35	0.35	0.34

Mitral E/A ratio

Variable used: ea_ratio

Additional label: E/A

Study	Normal	Decreased	Increased	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	3,036 (52.4%)	667 (11.5%)	698 (12.0%)	1,394 (24.1%)	5,795 (100.0%)
FHS	3,402 (24.4%)	613 (4.4%)	403 (2.9%)	9,550 (68.4%)	13,968 (100.0%)
JHS	1,810 (46.6%)	1,541 (39.7%)	62 (1.6%)	470 (12.1%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	8,248 (18.1%)	2,821 (6.2%)	1,163 (2.6%)	33,232 (73.1%)	45,464 (100.0%)

Mitral E/A ratio value

Variable used: ea_ratio_val

Additional label: E/A ratio

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	915	0.1	1.12	1.43	1.78	53.00	1.62	1.64
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	388	0.3	0.84	1.03	1.26	4.87	1.09	0.37
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	37089	0.1	0.97	1.24	1.57	53.00	1.40	1.30

Edema

Variable used: edema_px

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	13,889 (92.6%)	991 (6.6%)	124 (0.8%)	15,004 (100.0%)
CHS	4,794 (82.7%)	278 (4.8%)	723 (12.5%)	5,795 (100.0%)
FHS	0 (0.0%)	50 (0.4%)	13,918 (99.6%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	18,683 (41.1%)	1,319 (2.9%)	25,462 (56.0%)	45,464 (100.0%)

Edema - symptoms

Variable used: edema_sz

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	3,110 (53.7%)	1,977 (34.1%)	708 (12.2%)	5,795 (100.0%)
FHS	4,321 (30.9%)	570 (4.1%)	9,077 (65.0%)	13,968 (100.0%)
JHS	2,040 (52.5%)	1,802 (46.4%)	41 (1.1%)	3,883 (100.0%)
MESA	4,666 (68.5%)	2,126 (31.2%)	22 (0.3%)	6,814 (100.0%)
Total	14,137 (31.1%)	6,475 (14.2%)	24,852 (54.7%)	45,464 (100.0%)

Education level

Variable used: educ_level

Additional label: NA

Study	Associate/some college	Bachelors	Graduate	High school	Middle school	None	Some high school	Technical school	Technical School	Unknown	Total
ARIC	0 (0.0%)	3,832 (25.5%)	1,465 (9.8%)	4,861 (32.4%)	0 (0.0%)	1,458 (9.7%)	2,096 (14.0%)	1,267 (8.4%)	0 (0.0%)	25 (0.2%)	15,004 (100.0%)
CHS	0 (0.0%)	597 (10.3%)	575 (9.9%)	1,596 (27.5%)	895 (15.4%)	0 (0.0%)	812 (14.0%)	1,303 (22.5%)	0 (0.0%)	17 (0.3%)	5,795 (100.0%)
FHS	1,784 (12.8%)	1,971 (14.1%)	995 (7.1%)	2,101 (15.0%)	1,388 (9.9%)	35 (0.3%)	742 (5.3%)	0 (0.0%)	417 (3.0%)	4,535 (32.5%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	1,449 (21.3%)	1,171 (17.2%)	1,222 (17.9%)	1,236 (18.1%)	678 (10.0%)	71 (1.0%)	476 (7.0%)	488 (7.2%)	0 (0.0%)	23 (0.3%)	6,814 (100.0%)
Total	3,233 (7.1%)	7,571 (16.7%)	4,257 (9.4%)	9,794 (21.5%)	2,961 (6.5%)	1,564 (3.4%)	4,126 (9.1%)	3,058 (6.7%)	417 (0.9%)	8,483 (18.7%)	45,464 (100.0%)

Education level simple

Variable used: educ_level_simple

Additional label: NA

Study	Basic	High school	Higher learning	Unknown	Total
ARIC	3,554 (23.7%)	4,861 (32.4%)	6,564 (43.7%)	25 (0.2%)	15,004 (100.0%)
CHS	1,707 (29.5%)	1,596 (27.5%)	2,475 (42.7%)	17 (0.3%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	692 (17.8%)	803 (20.7%)	2,371 (61.1%)	17 (0.4%)	3,883 (100.0%)
MESA	1,225 (18.0%)	1,236 (18.1%)	4,330 (63.5%)	23 (0.3%)	6,814 (100.0%)
Total	7,178 (15.8%)	8,496 (18.7%)	15,740 (34.6%)	14,050 (30.9%)	45,464 (100.0%)

E/e prime lateral

Variable used: eeprime_lat

Additional label: E/e’ lateral

Study	Normal	Elevated	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	4,346 (31.1%)	24 (0.2%)	9,598 (68.7%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	4,346 (9.6%)	24 (0.1%)	41,094 (90.4%)	45,464 (100.0%)

E/e prime lateral value

Variable used: eeprime_lat_val

Additional label: E/e’ lateral

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	9598	2.35	4.85	5.63	6.65	17.33	5.92	1.55
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41094	2.35	4.85	5.63	6.65	17.33	5.92	1.55

LV ejection fraction category

Variable used: ef_cat

Additional label: EF

Study	pEF	mrEF	rEF	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	4,614 (79.6%)	274 (4.7%)	188 (3.2%)	719 (12.4%)	5,795 (100.0%)
FHS	470 (3.4%)	2 (0.0%)	1 (0.0%)	13,495 (96.6%)	13,968 (100.0%)
JHS	3,411 (87.8%)	66 (1.7%)	36 (0.9%)	370 (9.5%)	3,883 (100.0%)
MESA	4,918 (72.2%)	73 (1.1%)	13 (0.2%)	1,810 (26.6%)	6,814 (100.0%)
Total	13,413 (29.5%)	415 (0.9%)	238 (0.5%)	31,398 (69.1%)	45,464 (100.0%)

LV ejection fraction value

Variable used: ef_val

Additional label: EF, %

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	9779	23.52	61.56	63.84	66.03	81.29	63.70	3.89
JHS	3883	172	10.00	55.00	65.00	65.00	85.00	61.84	7.65
MESA	6814	1810	18.94	64.66	69.65	74.17	88.57	69.02	7.41
Overall	45464	32560	10.00	61.55	65.00	69.29	88.57	65.23	7.26

Eggs - daily servings

Variable used: eggs_val

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	359	0	0.09	0.32	0.66	4.43	0.55	0.64
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41940	0	0.09	0.32	0.66	4.43	0.55	0.64

Emotional social support index

Variable used: emot_support_idx

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	46	6	21	25	29	30	24.17	5.28
Overall	45464	38696	6	21	25	29	30	24.17	5.28

Alcohol use

Variable used: etoh

Additional label: EtOH

Study	No	Yes	Unknown	Total
ARIC	6,547 (43.6%)	8,389 (55.9%)	68 (0.5%)	15,004 (100.0%)
CHS	0 (0.0%)	2,887 (49.8%)	2,908 (50.2%)	5,795 (100.0%)
FHS	0 (0.0%)	3,390 (24.3%)	10,578 (75.7%)	13,968 (100.0%)
JHS	2,073 (53.4%)	1,789 (46.1%)	21 (0.5%)	3,883 (100.0%)
MESA	1,726 (25.3%)	3,749 (55.0%)	1,339 (19.7%)	6,814 (100.0%)
Total	10,346 (22.8%)	20,204 (44.4%)	14,914 (32.8%)	45,464 (100.0%)

E wave value

Variable used: ewave_val

Additional label: E wave

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	9546	29.41	61.51	69.82	78.29	128.91	70.02	12.48
JHS	3883	1407	5.20	7.40	8.30	9.10	16.00	8.42	1.34
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	38566	5.20	8.90	60.23	73.24	128.91	47.91	31.21

Family income classification

Variable used: family_income

Additional label: NA

Study	$12000-15999	$16000-19999	$20000-24999	$25000-29999	$25000-34999	$30000-34999	$35000-39999	$35000-49999	$40000-49999	$5000-7999	$50000-74999	$75000-99999	$8000-11999	<$5000	>$100,000	>$50,000	Unknown	Total
ARIC	1,035 (6.9%)	0 (0.0%)	2,126 (14.2%)	0 (0.0%)	2,535 (16.9%)	0 (0.0%)	0 (0.0%)	2,732 (18.2%)	0 (0.0%)	612 (4.1%)	0 (0.0%)	0 (0.0%)	837 (5.6%)	758 (5.1%)	0 (0.0%)	3,517 (23.4%)	852 (5.7%)	15,004 (100.0%)
CHS	846 (14.6%)	0 (0.0%)	1,062 (18.3%)	0 (0.0%)	829 (14.3%)	0 (0.0%)	0 (0.0%)	541 (9.3%)	0 (0.0%)	522 (9.0%)	0 (0.0%)	0 (0.0%)	647 (11.2%)	277 (4.8%)	0 (0.0%)	698 (12.0%)	373 (6.4%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	242 (6.2%)	212 (5.5%)	309 (8.0%)	0 (0.0%)	431 (11.1%)	0 (0.0%)	0 (0.0%)	499 (12.9%)	0 (0.0%)	173 (4.5%)	600 (15.5%)	270 (7.0%)	209 (5.4%)	117 (3.0%)	250 (6.4%)	0 (0.0%)	571 (14.7%)	3,883 (100.0%)
MESA	468 (6.9%)	324 (4.8%)	500 (7.3%)	391 (5.7%)	0 (0.0%)	468 (6.9%)	390 (5.7%)	0 (0.0%)	643 (9.4%)	254 (3.7%)	1,111 (16.3%)	598 (8.8%)	357 (5.2%)	157 (2.3%)	880 (12.9%)	0 (0.0%)	273 (4.0%)	6,814 (100.0%)
Total	2,591 (5.7%)	536 (1.2%)	3,997 (8.8%)	391 (0.9%)	3,795 (8.3%)	468 (1.0%)	390 (0.9%)	3,772 (8.3%)	643 (1.4%)	1,561 (3.4%)	1,711 (3.8%)	868 (1.9%)	2,050 (4.5%)	1,309 (2.9%)	1,130 (2.5%)	4,215 (9.3%)	16,037 (35.3%)	45,464 (100.0%)

Fasting blood glucose value

Variable used: fast_glucose

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	137	35	93	99.19	108.00	628	109.18	40.85
CHS	5795	79	53	94	101.00	112.00	657	111.32	37.47
FHS	13968	10073	39	70	79.00	88.00	420	81.98	22.05
JHS	3883	320	36	86	91.00	101.00	503	100.39	33.26
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	17423	35	89	97.00	106.89	657	104.72	38.37

Father living

Variable used: father_alive

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	11,567 (77.1%)	3,155 (21.0%)	282 (1.9%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	2,847 (73.3%)	898 (23.1%)	138 (3.6%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	14,414 (31.7%)	4,053 (8.9%)	26,997 (59.4%)	45,464 (100.0%)

Iron saturation

Variable used: fe_sat

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	72	2	21	27	34	101	28.04	10.7
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41653	2	21	27	34	101	28.04	10.7

Ferritin

Variable used: ferritin

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	72	14	64	124	222	3588	172.02	179.18
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41653	14	64	124	222	3588	172.02	179.18

Forced expiratory value - 1 second

Variable used: fev1

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	122	0.00	2.28	2.74	3.30	5.91	2.81	0.77
CHS	5795	757	0.30	1.63	2.04	2.49	4.47	2.08	0.66
FHS	13968	10160	1.08	3.01	3.49	4.15	6.47	3.59	0.79
JHS	3883	225	0.43	1.90	2.31	2.81	5.40	2.38	0.70
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	18078	0.00	2.12	2.65	3.27	6.47	2.73	0.87

FEV1/FVC class

Variable used: fev1_fvc_cat

Additional label: NA

Study	Abnormal	Normal	Unknown	Total
ARIC	11 (0.1%)	14,871 (99.1%)	122 (0.8%)	15,004 (100.0%)
CHS	0 (0.0%)	5,037 (86.9%)	758 (13.1%)	5,795 (100.0%)
FHS	0 (0.0%)	3,398 (24.3%)	10,570 (75.7%)	13,968 (100.0%)
JHS	334 (8.6%)	3,320 (85.5%)	229 (5.9%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	345 (0.8%)	26,626 (58.6%)	18,493 (40.7%)	45,464 (100.0%)

FEV1/FVC value

Variable used: fev1_fvc_val

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	122	0.00	70.62	75.59	79.53	100.00	74.25	8.40
CHS	5795	758	21.76	65.78	71.71	76.38	118.97	70.15	10.69
FHS	13968	10160	0.32	0.74	0.79	0.82	0.96	0.78	0.06
JHS	3883	225	0.13	0.77	0.82	0.86	17.24	0.81	0.29
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	18079	0.00	0.88	70.92	77.34	118.97	53.47	33.19

FEV1 % predicted severity

Variable used: fev1_pct_cat

Additional label: NA

Study	Mild-moderately abnormal	Normal	Severely abnormal	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	14,876 (99.1%)	128 (0.9%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,075 (87.6%)	720 (12.4%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	792 (20.4%)	2,809 (72.3%)	55 (1.4%)	227 (5.8%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	792 (1.7%)	2,809 (6.2%)	20,006 (44.0%)	21,857 (48.1%)	45,464 (100.0%)

FEV1 % predicted - value

Variable used: fev1_pct_val

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	128	0.00	0.83	0.95	1.05	1.70	0.93	0.17
CHS	5795	720	0.70	1.96	2.31	3.11	4.19	2.50	0.66
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	227	19.91	80.85	92.09	102.35	226.05	91.49	17.72
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	21857	0.00	0.90	1.07	2.46	226.05	15.29	33.36

Fish - daily servings

Variable used: fish_daily

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	359	0	0	0.09	0.17	10.51	0.19	0.46
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41940	0	0	0.09	0.17	10.51	0.19	0.46

Framingham Risk Score - CAD

Variable used: fram_cad

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	485	0.01	0.04	0.09	0.15	0.73	0.12	0.10
MESA	6814	0	0.00	0.02	0.08	0.16	30.00	3.13	8.36
Overall	45464	35252	0.00	0.03	0.08	0.16	30.00	2.12	6.97

Forced vital capacity

Variable used: fvc

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	122	0.00	3.07	3.67	4.45	8.25	3.79	1.00
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	10160	2.07	3.85	4.49	5.32	7.99	4.62	1.00
JHS	3883	225	0.29	2.37	2.85	3.50	9.38	2.97	0.85
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	23116	0.00	3.01	3.68	4.50	9.38	3.80	1.08

GED/HS

Variable used: ged

Additional label: NA

Study	Less than high school	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	641 (16.5%)	89 (2.3%)	3,153 (81.2%)	3,883 (100.0%)
MESA	1,154 (16.9%)	71 (1.0%)	4,344 (63.8%)	1,245 (18.3%)	6,814 (100.0%)
Total	1,154 (2.5%)	712 (1.6%)	4,433 (9.8%)	39,165 (86.1%)	45,464 (100.0%)

GED - partner

Variable used: ged_p

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	509 (13.1%)	44 (1.1%)	3,330 (85.8%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	509 (1.1%)	44 (0.1%)	44,911 (98.8%)	45,464 (100.0%)

Glucose

Variable used: glucose

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	79	53	94	101	112	657	111.32	37.47
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	39748	53	94	101	112	657	111.32	37.47

A1c value

Variable used: ha1c

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	143	3.6	5.3	5.7	6.2	16.1	6.01	1.31
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41724	3.6	5.3	5.7	6.2	16.1	6.01	1.31

Has healthcare coverage

Variable used: has_coverage

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	1,463 (9.8%)	13,508 (90.0%)	33 (0.2%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	517 (13.3%)	3,347 (86.2%)	19 (0.5%)	3,883 (100.0%)
MESA	609 (8.9%)	6,183 (90.7%)	22 (0.3%)	6,814 (100.0%)
Total	2,589 (5.7%)	23,038 (50.7%)	19,837 (43.6%)	45,464 (100.0%)

Hematocrit

Variable used: hct

Additional label: Hematocrit, %

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	229	17.3	39.0	41.7	44.5	61.6	41.73	4.04
CHS	5795	90	19.1	39.3	41.8	44.3	76.1	41.81	3.97
FHS	13968	10338	25.0	40.0	43.0	46.0	62.0	43.02	3.91
JHS	3883	137	0.0	36.6	39.2	42.0	57.2	39.29	4.29
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	17608	0.0	38.9	41.5	44.4	76.1	41.59	4.16

HDL category

Variable used: hdl_cat

Additional label: NA

Study	Abnormal	Borderline	Normal	Unknown	Total
ARIC	5,836 (38.9%)	4,994 (33.3%)	3,790 (25.3%)	384 (2.6%)	15,004 (100.0%)
CHS	1,682 (29.0%)	1,284 (22.2%)	354 (6.1%)	2,475 (42.7%)	5,795 (100.0%)
FHS	1,573 (11.3%)	1,561 (11.2%)	1,194 (8.5%)	9,640 (69.0%)	13,968 (100.0%)
JHS	1,314 (33.8%)	1,180 (30.4%)	837 (21.6%)	552 (14.2%)	3,883 (100.0%)
MESA	2,460 (36.1%)	2,451 (36.0%)	1,505 (22.1%)	398 (5.8%)	6,814 (100.0%)
Total	12,865 (28.3%)	11,470 (25.2%)	7,680 (16.9%)	13,449 (29.6%)	45,464 (100.0%)

HDL value

Variable used: hdl_val

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	233	9.63	39	48.15	60.67	163	51.41	17.08
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	344	19.00	41	50.00	60.00	143	51.78	14.74
MESA	6814	26	15.00	40	48.00	59.00	142	50.96	14.83
Overall	45464	20366	9.63	40	49.00	60.00	163	51.34	16.18

Heavy drinker

Variable used: heavy_etoh

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	2,438 (62.8%)	416 (10.7%)	1,029 (26.5%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	2,438 (5.4%)	416 (0.9%)	42,610 (93.7%)	45,464 (100.0%)

Height - cm

Variable used: height_cm

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	18	125.0	161.00	168.00	176.00	199.0	168.55	9.31
CHS	5795	11	151.0	157.97	164.30	172.00	181.0	164.91	8.84
FHS	13968	4740	48.0	62.75	65.25	68.25	78.0	65.45	3.75
JHS	3883	8	142.0	162.00	168.00	176.00	200.0	169.06	9.26
MESA	6814	0	141.3	158.90	166.00	173.50	195.4	166.36	9.97
Overall	45464	4777	48.0	151.00	163.00	172.00	200.0	144.33	43.57

Herbal tea - daily servings

Variable used: herbal_tea_daily

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	577	0	0	0	0.07	9	0.17	0.52
Overall	45464	39227	0	0	0	0.07	9	0.17	0.52

Heart failure

Variable used: hf

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	14,003 (93.3%)	726 (4.8%)	275 (1.8%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	14,003 (30.8%)	726 (1.6%)	30,735 (67.6%)	45,464 (100.0%)

Hemoglobin

Variable used: hgb

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	11009	7	12.4	13.5	14.4	18.7	13.47	1.46
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	42505	7	12.4	13.5	14.4	18.7	13.47	1.46

Hyperlipidemia

Variable used: hld

Additional label: HLD

Study	No	Yes	Unknown	Total
ARIC	11,428 (76.2%)	3,177 (21.2%)	399 (2.7%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	4,240 (62.2%)	2,538 (37.2%)	36 (0.5%)	6,814 (100.0%)
Total	15,668 (34.5%)	5,715 (12.6%)	24,081 (53.0%)	45,464 (100.0%)

HOMA-B value

Variable used: homa_b

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	1049	11.09	141.13	192.57	269.15	1405.57	222.75	127.6
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	42630	11.09	141.13	192.57	269.15	1405.57	222.75	127.6

HOMA-IR value

Variable used: homa_ir

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	1048	0.18	2.19	3.01	4.34	26.49	3.57	2.24
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	42629	0.18	2.19	3.01	4.34	26.49	3.57	2.24

Homocysteine

Variable used: homocys

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	84	3.3	7.3	8.7	10.6	92.4	9.47	3.95
MESA	6814	20	3.2	7.3	8.6	10.5	118.0	9.33	3.75
Overall	45464	34871	3.2	7.3	8.7	10.5	118.0	9.38	3.82

Heart rate

Variable used: hr

Additional label: HR, bpm

Study	< 60	100+	60-80	80-100	Unknown	Total
ARIC	3,674 (24.5%)	60 (0.4%)	9,015 (60.1%)	1,398 (9.3%)	857 (5.7%)	15,004 (100.0%)
CHS	5,778 (99.7%)	0 (0.0%)	2 (0.0%)	0 (0.0%)	15 (0.3%)	5,795 (100.0%)
FHS	717 (5.1%)	312 (2.2%)	4,673 (33.5%)	2,082 (14.9%)	6,184 (44.3%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	2,542 (37.3%)	4 (0.1%)	3,541 (52.0%)	309 (4.5%)	418 (6.1%)	6,814 (100.0%)
Total	12,711 (28.0%)	376 (0.8%)	17,231 (37.9%)	3,789 (8.3%)	11,357 (25.0%)	45,464 (100.0%)

Heart rate value

Variable used: hr_val

Additional label: HR

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	14	18	30	34	37	67	33.98	5.59
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	48	36	56	62	69	130	63.13	9.66
Overall	45464	32917	18	34	51	63	130	49.70	16.61

On hormone replacement therapy

Variable used: hrt

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	362 (6.2%)	5,433 (93.8%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	3,040 (78.3%)	617 (15.9%)	226 (5.8%)	3,883 (100.0%)
MESA	1,625 (23.8%)	1,647 (24.2%)	3,542 (52.0%)	6,814 (100.0%)
Total	4,665 (10.3%)	2,626 (5.8%)	38,173 (84.0%)	45,464 (100.0%)

Hypertension

Variable used: htn

Additional label: HTN

Study	No	Yes	Unknown	Total
ARIC	10,499 (70.0%)	4,418 (29.4%)	87 (0.6%)	15,004 (100.0%)
CHS	3,209 (55.4%)	2,579 (44.5%)	7 (0.1%)	5,795 (100.0%)
FHS	4,486 (32.1%)	108 (0.8%)	9,374 (67.1%)	13,968 (100.0%)
JHS	1,654 (42.6%)	2,227 (57.4%)	2 (0.1%)	3,883 (100.0%)
MESA	3,756 (55.1%)	3,058 (44.9%)	0 (0.0%)	6,814 (100.0%)
Total	23,604 (51.9%)	12,390 (27.3%)	9,470 (20.8%)	45,464 (100.0%)

Income status

Variable used: income_status

Additional label: NA

Study	Lower-middle	Poor	Upper-middle	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	824 (21.2%)	481 (12.4%)	1,000 (25.8%)	1,578 (40.6%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	824 (1.8%)	481 (1.1%)	1,000 (2.2%)	43,159 (94.9%)	45,464 (100.0%)

On insulin

Variable used: insulin

Additional label: Insulin

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,645 (97.4%)	138 (2.4%)	12 (0.2%)	5,795 (100.0%)
FHS	322 (2.3%)	4 (0.0%)	13,642 (97.7%)	13,968 (100.0%)
JHS	3,344 (86.1%)	254 (6.5%)	285 (7.3%)	3,883 (100.0%)
MESA	6,689 (98.2%)	122 (1.8%)	3 (0.0%)	6,814 (100.0%)
Total	16,000 (35.2%)	518 (1.1%)	28,946 (63.7%)	45,464 (100.0%)

Isovolumic relaxation time

Variable used: ivrt

Additional label: NA

Study	Normal	Decreased	Increased	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	1,646 (28.4%)	0 (0.0%)	4,149 (71.6%)	5,795 (100.0%)
FHS	488 (3.5%)	3,715 (26.6%)	125 (0.9%)	9,640 (69.0%)	13,968 (100.0%)
JHS	828 (21.3%)	306 (7.9%)	1,725 (44.4%)	1,024 (26.4%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	1,316 (2.9%)	5,667 (12.5%)	1,850 (4.1%)	36,631 (80.6%)	45,464 (100.0%)

Isovolumic relaxation time value

Variable used: ivrt_val

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	4149	0.01	0.06	0.08	0.11	11.93	1.39	3.20
FHS	13968	9586	4.00	42.00	52.00	63.00	140.00	53.03	17.31
JHS	3883	425	40.00	80.00	90.00	110.00	190.00	94.85	22.17
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	35978	0.01	37.00	60.00	85.00	190.00	59.32	37.15

Occupation

Variable used: job

Additional label: NA

Study	Construction	Farming	Homemaker	Management	Military	Production	Sales	Service	Sick	Unemployed	Unknown	Total
ARIC	1,477 (9.8%)	111 (0.7%)	1,474 (9.8%)	3,322 (22.1%)	0 (0.0%)	1,202 (8.0%)	2,968 (19.8%)	1,569 (10.5%)	0 (0.0%)	0 (0.0%)	2,881 (19.2%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	234 (6.0%)	5 (0.1%)	13 (0.3%)	1,346 (34.7%)	7 (0.2%)	592 (15.2%)	684 (17.6%)	964 (24.8%)	6 (0.2%)	9 (0.2%)	23 (0.6%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	1,711 (3.8%)	116 (0.3%)	1,487 (3.3%)	4,668 (10.3%)	7 (0.0%)	1,794 (3.9%)	3,652 (8.0%)	2,533 (5.6%)	6 (0.0%)	9 (0.0%)	29,481 (64.8%)	45,464 (100.0%)

LA end systolic area

Variable used: laa

Additional label: LAA

Study	Normal	Mild	Moderate	Severe	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	3,134 (80.7%)	564 (14.5%)	17 (0.4%)	1 (0.0%)	167 (4.3%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	3,134 (6.9%)	564 (1.2%)	17 (0.0%)	1 (0.0%)	41,748 (91.8%)	45,464 (100.0%)

LA volume index

Variable used: lav_ix

Additional label: LAV index

Study	Normal	Mild	Moderate	Severe	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	3,134 (80.7%)	564 (14.5%)	17 (0.4%)	1 (0.0%)	167 (4.3%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	3,134 (6.9%)	564 (1.2%)	17 (0.0%)	1 (0.0%)	41,748 (91.8%)	45,464 (100.0%)

LDL category

Variable used: ldl_cat

Additional label: NA

Study	Borderline	High	Optimal	Suboptimal	Unknown	Total
ARIC	4,191 (27.9%)	3,812 (25.4%)	2,305 (15.4%)	3,960 (26.4%)	736 (4.9%)	15,004 (100.0%)
CHS	1,613 (27.8%)	1,023 (17.7%)	1,127 (19.4%)	1,770 (30.5%)	262 (4.5%)	5,795 (100.0%)
FHS	958 (6.9%)	709 (5.1%)	937 (6.7%)	1,257 (9.0%)	10,107 (72.4%)	13,968 (100.0%)
JHS	885 (22.8%)	594 (15.3%)	829 (21.3%)	1,063 (27.4%)	512 (13.2%)	3,883 (100.0%)
MESA	1,445 (21.2%)	583 (8.6%)	1,945 (28.5%)	2,415 (35.4%)	426 (6.3%)	6,814 (100.0%)
Total	9,092 (20.0%)	6,721 (14.8%)	7,143 (15.7%)	10,465 (23.0%)	12,043 (26.5%)	45,464 (100.0%)

LDL value

Variable used: ldl_value

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	451	0	111.4	135.46	161.55	504.6	137.82	39.28
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	9929	27	101.0	124.00	150.00	394.0	127.33	37.08
JHS	3883	379	19	101.0	125.00	148.00	361.0	126.59	37.09
MESA	6814	113	12	96.0	116.00	136.00	315.0	117.20	31.46
Overall	45464	16667	0	104.0	127.00	153.00	504.6	130.19	37.97

Leptin

Variable used: leptin

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	90	0.8	10.1	22.9	39.6	291	28.1	23.87
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41671	0.8	10.1	22.9	39.6	291	28.1	23.87

Living with partner

Variable used: live_with_partner

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	1,450 (25.0%)	3,646 (62.9%)	699 (12.1%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	2,210 (56.9%)	1,659 (42.7%)	14 (0.4%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	3,660 (8.1%)	5,305 (11.7%)	36,499 (80.3%)	45,464 (100.0%)

Mother living

Variable used: living_m

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	8,178 (54.5%)	6,758 (45.0%)	68 (0.5%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	2,083 (53.6%)	1,746 (45.0%)	54 (1.4%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	10,261 (22.6%)	8,504 (18.7%)	26,699 (58.7%)	45,464 (100.0%)

On loop diuretic

Variable used: loop

Additional label: Loop diuretic

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,376 (92.8%)	407 (7.0%)	12 (0.2%)	5,795 (100.0%)
FHS	317 (2.3%)	8 (0.1%)	13,643 (97.7%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	6,677 (98.0%)	134 (2.0%)	3 (0.0%)	6,814 (100.0%)
Total	12,370 (27.2%)	549 (1.2%)	32,545 (71.6%)	45,464 (100.0%)

Lipoprotein a

Variable used: lpa

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	705	1	16	43	75	1378	53.85	55.05
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	193	9	25	47	81	316	58.95	45.65
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	36684	1	20	45	77	1378	55.99	51.37

LV diastolic diameter

Variable used: lvdd

Additional label: LVDd, cm

Study	Normal	Mild	Moderate	Severe	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	2,856 (49.3%)	305 (5.3%)	119 (2.1%)	68 (1.2%)	2,447 (42.2%)	5,795 (100.0%)
FHS	4,293 (30.7%)	75 (0.5%)	1 (0.0%)	0 (0.0%)	9,599 (68.7%)	13,968 (100.0%)
JHS	2,219 (57.1%)	200 (5.2%)	26 (0.7%)	15 (0.4%)	1,423 (36.6%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	9,368 (20.6%)	580 (1.3%)	146 (0.3%)	83 (0.2%)	35,287 (77.6%)	45,464 (100.0%)

LV diastolic diameter value

Variable used: lvdd_val

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	2444	2.83	4.49	4.89	5.35	9.94	4.95	0.69
FHS	13968	9596	3.59	4.63	4.92	5.19	6.87	4.92	0.41
JHS	3883	1407	37.20	46.80	49.60	52.30	78.60	49.69	4.47
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	35265	2.83	4.70	5.11	6.60	78.60	15.80	19.32

LV diastolic volume

Variable used: lvedv

Additional label: LV EDV, mL

Study	Normal	Mild	Moderate	Severe	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	2,128 (15.2%)	323 (2.3%)	105 (0.8%)	46 (0.3%)	11,366 (81.4%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	2,698 (39.6%)	1,046 (15.4%)	603 (8.8%)	655 (9.6%)	1,812 (26.6%)	6,814 (100.0%)
Total	4,826 (10.6%)	1,369 (3.0%)	708 (1.6%)	701 (1.5%)	37,860 (83.3%)	45,464 (100.0%)

LV diastolic volume value

Variable used: lvedv_val

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	9771	44.55	83.07	98.50	115.72	244.84	101.14	24.29
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	1810	44.67	104.39	122.48	145.50	290.04	126.37	31.52
Overall	45464	36263	44.55	92.78	110.75	133.30	290.04	114.86	31.10

LVH type

Variable used: lvh_type

Additional label: LV hypertrophy

Study	Normal	Concentric remodeling	Eccentric hypertropjy	Concentric hypertrophy	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	488 (8.4%)	51 (0.9%)	36 (0.6%)	5,220 (90.1%)	5,795 (100.0%)
FHS	0 (0.0%)	370 (2.6%)	199 (1.4%)	70 (0.5%)	13,329 (95.4%)	13,968 (100.0%)
JHS	2,132 (54.9%)	162 (4.2%)	112 (2.9%)	57 (1.5%)	1,420 (36.6%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	2,132 (4.7%)	1,020 (2.2%)	362 (0.8%)	163 (0.4%)	41,787 (91.9%)	45,464 (100.0%)

LV mass

Variable used: lvmass

Additional label: LV mass

Study	Normal	Mild	Moderate	Severe	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	2,412 (41.6%)	430 (7.4%)	247 (4.3%)	262 (4.5%)	2,444 (42.2%)	5,795 (100.0%)
FHS	3,222 (23.1%)	741 (5.3%)	257 (1.8%)	133 (1.0%)	9,615 (68.8%)	13,968 (100.0%)
JHS	1,813 (46.7%)	333 (8.6%)	153 (3.9%)	176 (4.5%)	1,408 (36.3%)	3,883 (100.0%)
MESA	4,623 (67.8%)	262 (3.8%)	83 (1.2%)	36 (0.5%)	1,810 (26.6%)	6,814 (100.0%)
Total	12,070 (26.5%)	1,766 (3.9%)	740 (1.6%)	607 (1.3%)	30,281 (66.6%)	45,464 (100.0%)

LV mass index

Variable used: lvmass_ix

Additional label: LV mass index, g/m2

Study	Normal	Mild	Moderate	Severe	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	3,256 (56.2%)	43 (0.7%)	26 (0.4%)	18 (0.3%)	2,452 (42.3%)	5,795 (100.0%)
FHS	4,099 (29.3%)	215 (1.5%)	40 (0.3%)	14 (0.1%)	9,600 (68.7%)	13,968 (100.0%)
JHS	3,359 (86.5%)	173 (4.5%)	67 (1.7%)	86 (2.2%)	198 (5.1%)	3,883 (100.0%)
MESA	4,798 (70.4%)	145 (2.1%)	43 (0.6%)	18 (0.3%)	1,810 (26.6%)	6,814 (100.0%)
Total	15,512 (34.1%)	576 (1.3%)	176 (0.4%)	136 (0.3%)	29,064 (63.9%)	45,464 (100.0%)

LV mass index value

Variable used: lvmass_ix_val

Additional label: LV mass index

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	2452	25.51	48.42	57.43	69.22	268.53	60.84	18.50
FHS	13968	9600	44.53	70.72	81.17	92.81	176.47	82.77	16.22
JHS	3883	198	19.09	61.22	70.82	84.14	375.14	74.98	21.63
MESA	6814	1810	27.95	66.68	75.93	86.75	229.98	77.96	16.33
Overall	45464	29064	19.09	61.88	73.16	86.04	375.14	75.08	19.65

LV posterior wall thickness

Variable used: lvpwd

Additional label: LVPWd, cm

Study	Normal	Mild	Moderate	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	4,131 (29.6%)	283 (2.0%)	8 (0.1%)	9,546 (68.3%)	13,968 (100.0%)
JHS	2,248 (57.9%)	164 (4.2%)	3 (0.1%)	1,468 (37.8%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	6,379 (14.0%)	447 (1.0%)	11 (0.0%)	38,627 (85.0%)	45,464 (100.0%)

LV posterior wall thickness value

Variable used: lvpwd_val

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	9493	0.6	0.81	0.88	0.97	1.64	0.90	0.12
JHS	3883	1407	5.2	7.40	8.30	9.10	16.00	8.42	1.34
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	38513	0.6	0.85	0.99	7.60	16.00	3.58	3.69

Lymphocytes - %

Variable used: lymphoc_pct

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	521	1	29	35.2	42	88	35.57	9.7
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	42102	1	29	35.2	42	88	35.57	9.7

Marital status

Variable used: marital_status

Additional label: NA

Study	Divorced	Married	Never married	Separated	Widowed	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	303 (5.2%)	3,820 (65.9%)	0 (0.0%)	0 (0.0%)	1,436 (24.8%)	236 (4.1%)	5,795 (100.0%)
FHS	516 (3.7%)	7,496 (53.7%)	1,574 (11.3%)	89 (0.6%)	282 (2.0%)	4,011 (28.7%)	13,968 (100.0%)
JHS	587 (15.1%)	2,122 (54.6%)	466 (12.0%)	167 (4.3%)	525 (13.5%)	16 (0.4%)	3,883 (100.0%)
MESA	922 (13.5%)	4,119 (60.4%)	558 (8.2%)	248 (3.6%)	893 (13.1%)	74 (1.1%)	6,814 (100.0%)
Total	2,328 (5.1%)	17,557 (38.6%)	2,598 (5.7%)	504 (1.1%)	3,136 (6.9%)	19,341 (42.5%)	45,464 (100.0%)

Has Medicaid

Variable used: medicaid

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	443 (3.2%)	21 (0.2%)	13,504 (96.7%)	13,968 (100.0%)
JHS	3,392 (87.4%)	467 (12.0%)	24 (0.6%)	3,883 (100.0%)
MESA	6,318 (92.7%)	474 (7.0%)	22 (0.3%)	6,814 (100.0%)
Total	10,153 (22.3%)	962 (2.1%)	34,349 (75.6%)	45,464 (100.0%)

Has Medicare

Variable used: medicare

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	387 (2.8%)	80 (0.6%)	13,501 (96.7%)	13,968 (100.0%)
JHS	0 (0.0%)	1,102 (28.4%)	2,781 (71.6%)	3,883 (100.0%)
MESA	4,355 (63.9%)	2,437 (35.8%)	22 (0.3%)	6,814 (100.0%)
Total	4,742 (10.4%)	3,619 (8.0%)	37,103 (81.6%)	45,464 (100.0%)

Menopause

Variable used: menopause

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	622 (4.1%)	5,992 (39.9%)	8,390 (55.9%)	15,004 (100.0%)
CHS	0 (0.0%)	3,329 (57.4%)	2,466 (42.6%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	272 (7.0%)	1,643 (42.3%)	1,968 (50.7%)	3,883 (100.0%)
MESA	503 (7.4%)	2,949 (43.3%)	3,362 (49.3%)	6,814 (100.0%)
Total	1,397 (3.1%)	13,913 (30.6%)	30,154 (66.3%)	45,464 (100.0%)

On metformin

Variable used: metformin

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,783 (99.8%)	0 (0.0%)	12 (0.2%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	6,475 (95.0%)	336 (4.9%)	3 (0.0%)	6,814 (100.0%)
Total	12,258 (27.0%)	336 (0.7%)	32,870 (72.3%)	45,464 (100.0%)

Magnesium - frequency

Variable used: mg_diet_freq

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	4577	0	360	1080	2520	25560	2094.45	3072.52
Overall	45464	43227	0	360	1080	2520	25560	2094.45	3072.52

Myocardial infarction

Variable used: mi

Additional label: MI

Study	No	Yes	Unknown	Total
ARIC	14,350 (95.6%)	599 (4.0%)	55 (0.4%)	15,004 (100.0%)
CHS	5,241 (90.4%)	554 (9.6%)	0 (0.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	19,591 (43.1%)	1,153 (2.5%)	24,720 (54.4%)	45,464 (100.0%)

Mitral regurgitation

Variable used: mitral_regurg

Additional label: MR

Study	Normal/Mild	Moderate/severe	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	4,378 (31.3%)	39 (0.3%)	9,551 (68.4%)	13,968 (100.0%)
JHS	3,625 (93.4%)	85 (2.2%)	173 (4.5%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	8,003 (17.6%)	124 (0.3%)	37,337 (82.1%)	45,464 (100.0%)

Matrix metalloproteinase 3

Variable used: mmp3

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	5815	2.26	8.02	11.73	18.49	123.11	15.65	14.58
Overall	45464	44465	2.26	8.02	11.73	18.49	123.11	15.65	14.58

Matrix metalloproteinase 6

Variable used: mmp6

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	5815	34.2	151.95	210.8	299.95	1351.6	245.33	142.48
Overall	45464	44465	34.2	151.95	210.8	299.95	1351.6	245.33	142.48

Neck circumference

Variable used: neck

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	7	29	36	38	41	55	38.65	3.78
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41588	29	36	38	41	55	38.65	3.78

On long-acting nitrate

Variable used: nitrate

Additional label: Nitrate

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,260 (90.8%)	523 (9.0%)	12 (0.2%)	5,795 (100.0%)
FHS	321 (2.3%)	5 (0.0%)	13,642 (97.7%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	6,800 (99.8%)	11 (0.2%)	3 (0.0%)	6,814 (100.0%)
Total	12,381 (27.2%)	539 (1.2%)	32,544 (71.6%)	45,464 (100.0%)

On NSAIDs

Variable used: nsaid

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,047 (87.1%)	736 (12.7%)	12 (0.2%)	5,795 (100.0%)
FHS	293 (2.1%)	32 (0.2%)	13,643 (97.7%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	5,622 (82.5%)	1,189 (17.4%)	3 (0.0%)	6,814 (100.0%)
Total	10,962 (24.1%)	1,957 (4.3%)	32,545 (71.6%)	45,464 (100.0%)

People in house

Variable used: num_people_home

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	8	1	2	2	3	9	2.76	1.26
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	30468	1	2	2	3	9	2.76	1.26

Oatmeal - daily servings

Variable used: oatmeal_daily

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	3883	NA	NA	NA	NA	NA	NA	NA
MESA	6814	577	0	0	0.04	0.25	3	0.17	0.28
Overall	45464	39227	0	0	0.04	0.25	3	0.17	0.28

Abdominal obesity

Variable used: obese_waist

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	7,024 (46.8%)	7,479 (49.8%)	501 (3.3%)	15,004 (100.0%)
CHS	3,001 (51.8%)	2,651 (45.7%)	143 (2.5%)	5,795 (100.0%)
FHS	2,956 (21.2%)	1,913 (13.7%)	9,099 (65.1%)	13,968 (100.0%)
JHS	1,310 (33.7%)	2,471 (63.6%)	102 (2.6%)	3,883 (100.0%)
MESA	3,090 (45.3%)	3,688 (54.1%)	36 (0.5%)	6,814 (100.0%)
Total	17,381 (38.2%)	18,202 (40.0%)	9,881 (21.7%)	45,464 (100.0%)

On oral hypoglycemic

Variable used: oral_hypog

Additional label: Oral hypoglycemic

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,411 (93.4%)	372 (6.4%)	12 (0.2%)	5,795 (100.0%)
FHS	319 (2.3%)	7 (0.1%)	13,642 (97.7%)	13,968 (100.0%)
JHS	3,163 (81.5%)	451 (11.6%)	269 (6.9%)	3,883 (100.0%)
MESA	6,223 (91.3%)	588 (8.6%)	3 (0.0%)	6,814 (100.0%)
Total	15,116 (33.2%)	1,418 (3.1%)	28,930 (63.6%)	45,464 (100.0%)

Orthopnea

Variable used: orthopnea

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	4,956 (85.5%)	803 (13.9%)	36 (0.6%)	5,795 (100.0%)
FHS	4,770 (34.1%)	114 (0.8%)	9,084 (65.0%)	13,968 (100.0%)
JHS	3,099 (79.8%)	744 (19.2%)	40 (1.0%)	3,883 (100.0%)
MESA	6,176 (90.6%)	610 (9.0%)	28 (0.4%)	6,814 (100.0%)
Total	19,001 (41.8%)	2,271 (5.0%)	24,192 (53.2%)	45,464 (100.0%)

Has other insurance

Variable used: other_insurance

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	423 (3.0%)	35 (0.3%)	13,510 (96.7%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	6,348 (93.2%)	444 (6.5%)	22 (0.3%)	6,814 (100.0%)
Total	6,771 (14.9%)	479 (1.1%)	38,214 (84.1%)	45,464 (100.0%)

Partner work status

Variable used: partner_work

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	145 (3.7%)	1,688 (43.5%)	2,050 (52.8%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	145 (0.3%)	1,688 (3.7%)	43,631 (96.0%)	45,464 (100.0%)

Paroxysmal nocturnal dyspnea

Variable used: pnd

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	13,188 (87.9%)	1,784 (11.9%)	32 (0.2%)	15,004 (100.0%)
CHS	5,087 (87.8%)	660 (11.4%)	48 (0.8%)	5,795 (100.0%)
FHS	4,732 (33.9%)	159 (1.1%)	9,077 (65.0%)	13,968 (100.0%)
JHS	3,202 (82.5%)	640 (16.5%)	41 (1.1%)	3,883 (100.0%)
MESA	6,038 (88.6%)	719 (10.6%)	57 (0.8%)	6,814 (100.0%)
Total	32,247 (70.9%)	3,962 (8.7%)	9,255 (20.4%)	45,464 (100.0%)

Population density per square mile

Variable used: pop_per_mile

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	6	4.19	1109.57	2210.6	3268.19	4410.03	2148.58	1269.25
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41587	4.19	1109.57	2210.6	3268.19	4410.03	2148.58	1269.25

Percent below poverty line

Variable used: poverty_pct

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	6	0.01	0.12	0.27	0.34	0.55	0.24	0.13
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41587	0.01	0.12	0.27	0.34	0.55	0.24	0.13

Preeclampsia/toxemia

Variable used: preeclmpsia

Additional label: NA

Study	Yes	Unknown	Total
ARIC	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	208 (1.5%)	13,760 (98.5%)	13,968 (100.0%)
JHS	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	208 (0.5%)	45,256 (99.5%)	45,464 (100.0%)

Has private insurance

Variable used: private_insurance

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	104 (0.7%)	386 (2.8%)	13,478 (96.5%)	13,968 (100.0%)
JHS	0 (0.0%)	2,486 (64.0%)	1,397 (36.0%)	3,883 (100.0%)
MESA	2,083 (30.6%)	4,709 (69.1%)	22 (0.3%)	6,814 (100.0%)
Total	2,187 (4.8%)	7,581 (16.7%)	35,696 (78.5%)	45,464 (100.0%)

Heart rate variability - SDNN

Variable used: sdnn

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	90	1	13.7	22.3	36.5	584.9	32.42	36.68
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41671	1	13.7	22.3	36.5	584.9	32.42	36.68

Census Tract SES Score

Variable used: ses

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	6	-2.23	0.24	0.75	1.15	1.65	0.64	0.65
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41587	-2.23	0.24	0.75	1.15	1.65	0.64	0.65

Number of siblings

Variable used: siblings

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	93	0	2	5	8	24	5.07	3.72
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41674	0	2	5	8	24	5.07	3.72

Hours of sleep

Variable used: sleep_hrs_val

Additional label: NA

Study	n	n_missing	min	Q1	median	Q3	max	mean	std
ARIC	15004	15004	NA	NA	NA	NA	NA	NA	NA
CHS	5795	5795	NA	NA	NA	NA	NA	NA	NA
FHS	13968	13968	NA	NA	NA	NA	NA	NA	NA
JHS	3883	28	1	6	6	7	18	6.43	1.52
MESA	6814	6814	NA	NA	NA	NA	NA	NA	NA
Overall	45464	41609	1	6	6	7	18	6.43	1.52

Loud snoring

Variable used: snoring

Additional label: NA

Study	Almost always	Never	Often	Seldom	Sometimes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	317 (8.2%)	1,483 (38.2%)	347 (8.9%)	564 (14.5%)	1,147 (29.5%)	25 (0.6%)	3,883 (100.0%)
MESA	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	6,814 (100.0%)	6,814 (100.0%)
Total	317 (0.7%)	1,483 (3.3%)	347 (0.8%)	564 (1.2%)	1,147 (2.5%)	41,606 (91.5%)	45,464 (100.0%)

On statin

Variable used: statin

Additional label: Statin

Study	No	Yes	Unknown	Total
ARIC	14,803 (98.7%)	86 (0.6%)	115 (0.8%)	15,004 (100.0%)
CHS	5,656 (97.6%)	127 (2.2%)	12 (0.2%)	5,795 (100.0%)
FHS	310 (2.2%)	16 (0.1%)	13,642 (97.7%)	13,968 (100.0%)
JHS	3,312 (85.3%)	533 (13.7%)	38 (1.0%)	3,883 (100.0%)
MESA	5,802 (85.1%)	1,009 (14.8%)	3 (0.0%)	6,814 (100.0%)
Total	29,883 (65.7%)	1,771 (3.9%)	13,810 (30.4%)	45,464 (100.0%)

On thiazide diuretic

Variable used: thiazide

Additional label: Thiazide

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	1,126 (19.4%)	4,669 (80.6%)	5,795 (100.0%)
FHS	314 (2.2%)	11 (0.1%)	13,643 (97.7%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	0 (0.0%)	758 (11.1%)	6,056 (88.9%)	6,814 (100.0%)
Total	314 (0.7%)	1,895 (4.2%)	43,255 (95.1%)	45,464 (100.0%)

On thiazolidinediones

Variable used: tzd

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,783 (99.8%)	0 (0.0%)	12 (0.2%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	6,708 (98.4%)	103 (1.5%)	3 (0.0%)	6,814 (100.0%)
Total	12,491 (27.5%)	103 (0.2%)	32,870 (72.3%)	45,464 (100.0%)

Has VA coverage

Variable used: va_coverage

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	0 (0.0%)	0 (0.0%)	5,795 (100.0%)	5,795 (100.0%)
FHS	456 (3.3%)	7 (0.1%)	13,505 (96.7%)	13,968 (100.0%)
JHS	0 (0.0%)	291 (7.5%)	3,592 (92.5%)	3,883 (100.0%)
MESA	6,547 (96.1%)	245 (3.6%)	22 (0.3%)	6,814 (100.0%)
Total	7,003 (15.4%)	543 (1.2%)	37,918 (83.4%)	45,464 (100.0%)

On vasodilator

Variable used: vadodilator

Additional label: NA

Study	No	Yes	Unknown	Total
ARIC	0 (0.0%)	0 (0.0%)	15,004 (100.0%)	15,004 (100.0%)
CHS	5,343 (92.2%)	440 (7.6%)	12 (0.2%)	5,795 (100.0%)
FHS	326 (2.3%)	0 (0.0%)	13,642 (97.7%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	6,493 (95.3%)	318 (4.7%)	3 (0.0%)	6,814 (100.0%)
Total	12,162 (26.8%)	758 (1.7%)	32,544 (71.6%)	45,464 (100.0%)

On oral anticoagulation

Variable used: warfarin

Additional label: Warfarin

Study	No	Yes	Unknown	Total
ARIC	14,803 (98.7%)	86 (0.6%)	115 (0.8%)	15,004 (100.0%)
CHS	5,686 (98.1%)	97 (1.7%)	12 (0.2%)	5,795 (100.0%)
FHS	0 (0.0%)	0 (0.0%)	13,968 (100.0%)	13,968 (100.0%)
JHS	0 (0.0%)	0 (0.0%)	3,883 (100.0%)	3,883 (100.0%)
MESA	6,787 (99.6%)	24 (0.4%)	3 (0.0%)	6,814 (100.0%)
Total	27,276 (60.0%)	207 (0.5%)	17,981 (39.5%)	45,464 (100.0%)